Synthon Headquarters

Synthon's headquarters are located in Nijmegen, the Netherlands. This 36,000 m2 location accommodates research and development facilities for our Biopharmaceuticals business. In addition, the site handles the central management of our Generics business, covering all responsibilities related to the core process:

  • Strategic and project management for R&D activities
  • Intellectual property expertise
  • Regulatory affairs competence
  • Medical research & development
  • Commercial division

These activities are supported by a high-quality service organization, including Information Services, Finance & Accounting, Human Resources and Legal Affairs. The Nijmegen facility is home to 500 employees from more than 30 nationalities.

In 2017 and 2019, Synthon Nijmegen was named a Best Workplace® according to the Dutch Great Place to Work Institute®. In 2019, Synthon achieved an honorable 9th place in the list of Top 10 Best Multinational Workplaces in the Netherlands.  

Robust state-of-the-art infrastructure

In recent years Synthon has ramped up its investments in its biopharmaceutical infrastructure at its HQ campus in Nijmegen. Synthon now has all the facilities necessary for process development right up to large-scale production. Infrastructure highlights include:

Monoclonal antibody plant
  • ultramodern GMP plant for the production of therapeutic monoclonal antibodies (mAbs)
  • flexible multi-product plant 
  • manufacturing capability comprising dual 2,000L bioreactors based on single-use technologies
Antibody-drug conjugation facility
  • facility includes high-potent clean room suite and supporting areas for buffer preparation and in-process control testing
  • inspected and approved by the Dutch authorities for manufacturing and release of ADC material and Investigational Medicinal Product for use in clinical programs
  • the highly potent linker-drugs for our ADCs are manufactured at the facilities of our center of excellence for chemical APIs in the Czech Republic, an outstanding example of the synergy within the Synthon Group bridging small molecules and biotech proteins
Main R&D building Biopharmaceuticals
  • two floors each with 1,000 m2 of laboratory space
  • a total 2,400 m2 office space, housing the majority of Biopharmaceuticals’ R&D staff
  • the building also contains 800 m2 GMP warehouse

Quality and compliance

We develop and use advanced analytical technologies to design efficient manufacturing processes and to deeply characterize and control our products from a chemical, physical and biological perspective. High-quality standards are enforced by bringing science and compliance closely together in our ultramodern manufacturing facilities and quality control laboratories.

Synthon Biopharmaceuticals has been certified by the Dutch Healthcare Inspectorate (IGZ) for the manufacturing, quality control testing and release of Investigational Medicinal Products.

Future requirements

Recently initiated activities to expand our production capacity for (high-potent) active pharmaceutical ingredients at our Czech facilities will also meet our future requirements for the manufacturing of new chemical entities.

Where to find us

Synthon BV & 
Synthon Biopharmaceuticals BV

Microweg 22
P.O. Box 7071
6503 GN Nijmegen, the Netherlands

T (+31) 24 372 77 00

Synthon BV
VAT number: NL8001.00.517.B.01
Chamber of Commerce: 10036060

Synthon Biopharmaceuticals BV
VAT number: NL8511.30.975.B.01
Chamber of Commerce: 54042577

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